8QFX
Human Angiotensin-1 converting enzyme N-domain in complex with the lactotripeptide IPP
Summary for 8QFX
| Entry DOI | 10.2210/pdb8qfx/pdb |
| Descriptor | Angiotensin-converting enzyme, soluble form, DODECAETHYLENE GLYCOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ... (20 entities in total) |
| Functional Keywords | inhibitor, complex, angiotensin i coverting enzyme, metalloprotease, lactotripeptide, hydrolase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 303892.07 |
| Authors | Gregory, K.S.,Acharya, K.R.,Cozier, G.E. (deposition date: 2023-09-05, release date: 2023-11-22, Last modification date: 2024-02-07) |
| Primary citation | Gregory, K.S.,Cozier, G.E.,Schwager, S.L.U.,Sturrock, E.D.,Acharya, K.R. Structural insights into the inhibitory mechanism of angiotensin-I-converting enzyme by the lactotripeptides IPP and VPP. Febs Lett., 598:242-251, 2024 Cited by PubMed: 37904282DOI: 10.1002/1873-3468.14768 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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