8QDH
Engineered LmrR carrying a cyclic boronate ester formed between Tris and p-boronophenylalanine at position 89
Summary for 8QDH
| Entry DOI | 10.2210/pdb8qdh/pdb |
| Descriptor | Transcriptional regulator, PadR-like family, GLYCEROL (3 entities in total) |
| Functional Keywords | artificial enzyme, boron catalysis, unnatural amino acid, 4-boronophenylalanine, transcription |
| Biological source | Lactococcus cremoris subsp. cremoris MG1363 |
| Total number of polymer chains | 2 |
| Total formula weight | 30822.19 |
| Authors | Thunnissen, A.M.W.H.,Rozeboom, H.J.,Longwitz, L.,Leveson-Gower, R.B.,Roelfes, G. (deposition date: 2023-08-29, release date: 2024-05-01, Last modification date: 2024-06-05) |
| Primary citation | Longwitz, L.,Leveson-Gower, R.B.,Rozeboom, H.J.,Thunnissen, A.W.H.,Roelfes, G. Boron catalysis in a designer enzyme. Nature, 629:824-829, 2024 Cited by PubMed: 38720081DOI: 10.1038/s41586-024-07391-3 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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