8QBD

Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol, PI(4,5)P2 35:20:20:15:10)

Summary for 8QBD

Entry DOI	10.2210/pdb8qbd/pdb
EMDB information	18310
Descriptor	Sphingolipid long chain base-responsive protein PIL1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine (3 entities in total)
Functional Keywords	bar domain, lipid reconstitution, membrane microdomain, lipid binding protein
Biological source	Saccharomyces cerevisiae (brewer's yeast)
Total number of polymer chains	14
Total formula weight	554473.00
Authors	Kefauver, J.M.,Zou, L.,Desfosses, A.,Loewith, R.J. (deposition date: 2023-08-24, release date: 2024-07-24, Last modification date: 2024-08-07)
Primary citation	Kefauver, J.M.,Hakala, M.,Zou, L.,Alba, J.,Espadas, J.,Tettamanti, M.G.,Gajic, J.,Gabus, C.,Campomanes, P.,Estrozi, L.F.,Sen, N.E.,Vanni, S.,Roux, A.,Desfosses, A.,Loewith, R. Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 2024 Cited by PubMed: 39048819 DOI: 10.1038/s41586-024-07720-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.61 Å)

Structure validation