8QBB
Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10)
Summary for 8QBB
Entry DOI | 10.2210/pdb8qbb/pdb |
EMDB information | 18309 |
Descriptor | Sphingolipid long chain base-responsive protein PIL1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (2 entities in total) |
Functional Keywords | bar domain, lipid reconstitution, membrane microdomain, lipid binding protein |
Biological source | Saccharomyces cerevisiae (brewer's yeast) |
Total number of polymer chains | 14 |
Total formula weight | 543383.95 |
Authors | Kefauver, J.M.,Zou, L.,Desfosses, A.,Loewith, R.J. (deposition date: 2023-08-24, release date: 2024-07-24, Last modification date: 2024-08-07) |
Primary citation | Kefauver, J.M.,Hakala, M.,Zou, L.,Alba, J.,Espadas, J.,Tettamanti, M.G.,Gajic, J.,Gabus, C.,Campomanes, P.,Estrozi, L.F.,Sen, N.E.,Vanni, S.,Roux, A.,Desfosses, A.,Loewith, R. Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 2024 Cited by PubMed: 39048819DOI: 10.1038/s41586-024-07720-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.86 Å) |
Structure validation
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