8QAE

X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix alpha-helical barrel, sc-apCC-6-SLLA

Summary for 8QAE

• Entry DOI: 10.2210/pdb8qae/pdb
• Descriptor: sc-apCC-6-SLLA, 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, PENTAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: coiled coil, alpha-helical barrel, de novo protein design, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 53223.66

Authors

Albanese, K.I.,Petrenas, R.,Woolfson, D.N. (deposition date: 2023-08-22, release date: 2024-07-03)

• Primary citation: Albanese, K.I.,Petrenas, R.,Pirro, F.,Naudin, E.A.,Borucu, U.,Dawson, W.M.,Scott, D.A.,Leggett, G.J.,Weiner, O.D.,Oliver, T.A.A.,Woolfson, D.N.; Rationally seeded computational protein design of ɑ-helical barrels.; Nat.Chem.Biol., 2024; PubMed: 38902458; DOI: 10.1038/s41589-024-01642-0

Experimental method

X-RAY DIFFRACTION (1.9 Å)