8QA2

Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation

Summary for 8QA2

Entry DOI	10.2210/pdb8qa2/pdb
EMDB information	18293
Descriptor	Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE (3 entities in total)
Functional Keywords	gap junction large pore channel carbon dioxide sensitive, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	12
Total formula weight	330106.59
Authors	Brotherton, D.H.,Cameron, A.D. (deposition date: 2023-08-22, release date: 2024-06-12, Last modification date: 2024-06-19)
Primary citation	Brotherton, D.H.,Nijjar, S.,Savva, C.G.,Dale, N.,Cameron, A.D. Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13:-, 2024 Cited by PubMed: 38829031 DOI: 10.7554/eLife.93686 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.3 Å)

Structure validation