8Q9S

STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR SGC-CK2-1

Summary for 8Q9S

Entry DOI	10.2210/pdb8q9s/pdb
Descriptor	Casein kinase II subunit alpha', ~{N}-[5-[[3-cyano-7-(cyclopropylamino)-3~{H}-pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]propanamide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	protein kinase ck2 casein kinase 2 inhibitor sgc-ck2-1, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43379.43
Authors	Werner, C.,Lindenblatt, D.,Niefind, K. (deposition date: 2023-08-21, release date: 2023-12-06)
Primary citation	Werner, C.,Lindenblatt, D.,Viht, K.,Uri, A.,Niefind, K. Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool Kinases Phosphatases, 2023 Cited by DOI: 10.3390/kinasesphosphatases1040018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.352 Å)

Structure validation