8Q9S

STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR SGC-CK2-1

8Q9S の概要

• エントリーDOI: 10.2210/pdb8q9s/pdb
• 分子名称: Casein kinase II subunit alpha', ~{N}-[5-[[3-cyano-7-(cyclopropylamino)-3~{H}-pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]propanamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: protein kinase ck2 casein kinase 2 inhibitor sgc-ck2-1, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43379.43

構造登録者

Werner, C.,Lindenblatt, D.,Niefind, K. (登録日: 2023-08-21, 公開日: 2023-12-06)

• 主引用文献: Werner, C.,Lindenblatt, D.,Viht, K.,Uri, A.,Niefind, K.; Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool; Kinases Phosphatases, 2023; DOI: 10.3390/kinasesphosphatases1040018

実験手法

X-RAY DIFFRACTION (1.352 Å)