8Q9R

Crystal structure of MADS-box/MEF2D N-terminal domain bound to dsDNA and HDAC9 deacetylase binding motif

8Q9R の概要

• エントリーDOI: 10.2210/pdb8q9r/pdb
• 分子名称: Histone deacetylase 9 (HDAC9) binding motif peptide: EVKQKLQEFLLSKS, MEF2D protein, MADS box dsDNA: AACTATTTATAAGA, ... (5 entities in total)
• 機能のキーワード: transcriptional regulator, transcription
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 66262.18

構造登録者

Chinellato, M.,Carli, A.,Perin, S.,Mazzoccato, Y.,Di Giorgio, E.,Brancolini, C.,Angelini, A.,Cendron, L. (登録日: 2023-08-20, 公開日: 2024-04-17)

• 主引用文献: Chinellato, M.,Perin, S.,Carli, A.,Lastella, L.,Biondi, B.,Borsato, G.,Di Giorgio, E.,Brancolini, C.,Cendron, L.,Angelini, A.; Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.; J.Mol.Biol., 436:168541-168541, 2024; PubMed: 38492719; DOI: 10.1016/j.jmb.2024.168541

実験手法

X-RAY DIFFRACTION (2.25 Å)