8Q7E
Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
Summary for 8Q7E
Entry DOI | 10.2210/pdb8q7e/pdb |
Related | 8Q7H |
EMDB information | 18214 18220 18221 18222 18223 |
Descriptor | Cullin-9, E3 ubiquitin-protein ligase RBX1 (2 entities in total) |
Functional Keywords | cullin-ring rbr e3 ligase, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 1762931.11 |
Authors | Hopf, L.V.M.,Horn-Ghetko, D.,Schulman, B.A. (deposition date: 2023-08-16, release date: 2024-04-17, Last modification date: 2024-07-31) |
Primary citation | Horn-Ghetko, D.,Hopf, L.V.M.,Tripathi-Giesgen, I.,Du, J.,Kostrhon, S.,Vu, D.T.,Beier, V.,Steigenberger, B.,Prabu, J.R.,Stier, L.,Bruss, E.M.,Mann, M.,Xiong, Y.,Schulman, B.A. Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31:1083-1094, 2024 Cited by PubMed: 38605244DOI: 10.1038/s41594-024-01257-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
Download full validation report