8Q5R
HpARI bound to mouse IL-33
Summary for 8Q5R
Entry DOI | 10.2210/pdb8q5r/pdb |
Descriptor | Interleukin-33, Alarmin release inhibitor, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | helminth; il-33; anti-allergy; anti-inflammatory, immunosuppressant |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 43605.67 |
Authors | Jamwal, A.,Higgins, M.K. (deposition date: 2023-08-09, release date: 2024-05-08, Last modification date: 2024-07-03) |
Primary citation | Jamwal, A.,Colomb, F.,McSorley, H.J.,Higgins, M.K. Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2. Nat Commun, 15:5226-5226, 2024 Cited by PubMed: 38890291DOI: 10.1038/s41467-024-49550-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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