8Q5O
N-terminal domain of restriction endonuclease Eco15I with tetra-methylated target DNA.
Summary for 8Q5O
Entry DOI | 10.2210/pdb8q5o/pdb |
Descriptor | Restriction endonuclease (Eco15I), DNA (5'-D(*CP*TP*GP*(5CM)P*TP*GP*(5CM)P*TP*C)-3'), DNA (5'-D(*GP*AP*GP*(5CM)P*AP*GP*(5CM)P*AP*G)-3'), ... (5 entities in total) |
Functional Keywords | methylation-dependent restriction enzyme, dna methylation, restriction of modified phage dna, bisi family endonucleases, 5-methylcytosine recognition, type ii restriction endonucleases, modification-specific restriction enzyme, hydrolase |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 44152.04 |
Authors | Rafalski, D.,Krakowska, K.,Bochtler, M. (deposition date: 2023-08-09, release date: 2024-07-17, Last modification date: 2024-09-04) |
Primary citation | Szafran, K.,Rafalski, D.,Skowronek, K.,Wojciechowski, M.,Kazrani, A.A.,Gilski, M.,Xu, S.Y.,Bochtler, M. Structural analysis of the BisI family of modification dependent restriction endonucleases. Nucleic Acids Res., 52:9103-9118, 2024 Cited by PubMed: 39041409DOI: 10.1093/nar/gkae634 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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