8Q1K

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

8Q1K の概要

• エントリーDOI: 10.2210/pdb8q1k/pdb
• 分子名称: 5'-3' exonuclease PLD3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: pld3, structural biology, lysosome, dna/rna degradation, phospholipase d, 5' exonuclease, dna binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98624.54

構造登録者

Roske, Y.,Daumke, O.,Damme, M. (登録日: 2023-07-31, 公開日: 2023-12-06, 最終更新日: 2024-01-24)

• 主引用文献: Roske, Y.,Cappel, C.,Cremer, N.,Hoffmann, P.,Koudelka, T.,Tholey, A.,Heinemann, U.,Daumke, O.,Damme, M.; Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.; Nucleic Acids Res., 52:370-384, 2024; PubMed: 37994783; DOI: 10.1093/nar/gkad1114

実験手法