8Q19
The Crystal Structure of Human Carbonic Anhydrase IX in Complex with Sulfonamide
Summary for 8Q19
| Entry DOI | 10.2210/pdb8q19/pdb |
| Descriptor | Carbonic anhydrase 9, ZINC ION, 2-but-2-ynyl-1,1,3-tris(oxidanylidene)-1,2-benzothiazole-6-sulfonamide, ... (5 entities in total) |
| Functional Keywords | ca ix, ca 9, carbonic anhydrase ix, carbonic anhydrase 9, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 114634.21 |
| Authors | Leitans, J.,Tars, K. (deposition date: 2023-07-31, release date: 2023-11-08, Last modification date: 2023-12-06) |
| Primary citation | Leitans, J.,Kazaks, A.,Bogans, J.,Supuran, C.T.,Akopjana, I.,Ivanova, J.,Zalubovskis, R.,Tars, K. Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX. Chemmedchem, 18:e202300454-e202300454, 2023 Cited by PubMed: 37837260DOI: 10.1002/cmdc.202300454 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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