8PZM
Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 bound to bestatin inhibitor and manganese
Summary for 8PZM
Entry DOI | 10.2210/pdb8pzm/pdb |
Related | 8PZO |
Descriptor | Probable cytosol aminopeptidase, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | aminopeptidase, metalloenzyme, hexamer, hydrolase, bestatin, inhibitor, manganese |
Biological source | Pseudomonas aeruginosa PA14 |
Total number of polymer chains | 1 |
Total formula weight | 55660.64 |
Authors | Simpson, M.C.,Czekster, C.M.,Harding, C.J. (deposition date: 2023-07-27, release date: 2023-11-15, Last modification date: 2023-12-06) |
Primary citation | Simpson, M.C.,Harding, C.J.,Czekster, R.M.,Remmel, L.,Bode, B.E.,Czekster, C.M. Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry, 62:3188-3205, 2023 Cited by PubMed: 37924287DOI: 10.1021/acs.biochem.3c00420 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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