8PVS

Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood

This is a non-PDB format compatible entry.

Summary for 8PVS

• Entry DOI: 10.2210/pdb8pvs/pdb
• Descriptor: Alpha-1,3-galactosidase B, alpha-D-galactopyranose, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: alpha-galactosidase, akkermansia muciniphila, blood conversion, beta-helix, hydrolase
• Biological source: Akkermansia muciniphila
• Total number of polymer chains: 2
• Total formula weight: 162863.71

Authors

Jensen, M.,Abou Hachem, M.,Morth, J.P. (deposition date: 2023-07-18, release date: 2024-02-28, Last modification date: 2024-05-15)

• Primary citation: Jensen, M.,Stenfelt, L.,Ricci Hagman, J.,Pichler, M.J.,Weikum, J.,Nielsen, T.S.,Hult, A.,Morth, J.P.,Olsson, M.L.,Abou Hachem, M.; Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood.; Nat Microbiol, 2024; PubMed: 38684911; DOI: 10.1038/s41564-024-01663-4

Experimental method

X-RAY DIFFRACTION (1.68 Å)