8PVR

Cryo-EM structure of horse Nhe9 bound to PI(3,5)P2

Summary for 8PVR

• Entry DOI: 10.2210/pdb8pvr/pdb
• EMDB information: 17971
• Descriptor: Sodium/hydrogen exchanger 9, (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate (2 entities in total)
• Functional Keywords: na+/h+ exchanger, membrane protein, slc9a9, ion transporter, pi(3, 5)p2, transport protein
• Biological source: Equus caballus (horse)
• Total number of polymer chains: 2
• Total formula weight: 131205.24

Authors

Kokane, S.,Meier, P.,Gulati, A.,Delemotte, L.,Drew, D. (deposition date: 2023-07-18, release date: 2024-07-24)

• Primary citation: Kokane, S.,Meier, P.,Gulati, A.,Matsuoka, R.,Pipatpolkai, T.,Delemotte, L.,Drew, D.; PIP2 mediated oligomerization of the endosomal sodium/proton exchanger NHE9; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.06 Å)