8PTH

Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (open core | partial replicase conformation)

Summary for 8PTH

Entry DOI	10.2210/pdb8pth/pdb
EMDB information	17871
Descriptor	Polymerase acidic protein (PA-like), Putative PB1, RNA-dependent RNA polymerase, ... (6 entities in total)
Functional Keywords	viral polymerase, viral protein
Biological source	Tilapia lake virus More
Total number of polymer chains	5
Total formula weight	184280.47
Authors	Arragain, B.,Cusack, S. (deposition date: 2023-07-14, release date: 2023-12-27)
Primary citation	Arragain, B.,Pelosse, M.,Thompson, A.,Cusack, S. Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14:8145-8145, 2023 Cited by PubMed: 38066000 DOI: 10.1038/s41467-023-44044-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.73 Å)

Structure validation