8PRW

Cryo-EM structure of the yeast fatty acid synthase at 1.9 angstrom resolution

This is a non-PDB format compatible entry.

Summary for 8PRW

• Entry DOI: 10.2210/pdb8prw/pdb
• EMDB information: 17840
• Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• Functional Keywords: fatty acid synthase, acyl carrier protein, fas, acp, cytosolic protein
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 12
• Total formula weight: 2633541.19

Authors

Singh, K.,Bunzel, G.,Graf, B.,Yip, K.M.,Stark, H.,Chari, A. (deposition date: 2023-07-12, release date: 2023-11-22)

• Primary citation: Singh, K.,Bunzel, G.,Graf, B.,Yip, K.M.,Neumann-Schaal, M.,Stark, H.,Chari, A.; Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.; Cell, 186:5054-5067.e16, 2023; PubMed: 37949058; DOI: 10.1016/j.cell.2023.10.009

Experimental method

ELECTRON MICROSCOPY (1.9 Å)