8PQW
Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1
Summary for 8PQW
Entry DOI | 10.2210/pdb8pqw/pdb |
EMDB information | 17826 |
Descriptor | Cytoplasmic dynein 1 heavy chain 1, Platelet-activating factor acetylhydrolase IB subunit beta, Dynactin subunit 1, ... (7 entities in total) |
Functional Keywords | dynein, aaa-atpase, p150, lis1, motor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 1142647.71 |
Authors | Singh, K.,Lau, C.K.,Manigrasso, G.,Gassmann, R.,Carter, A.P. (deposition date: 2023-07-12, release date: 2024-03-27, Last modification date: 2024-04-10) |
Primary citation | Singh, K.,Lau, C.K.,Manigrasso, G.,Gama, J.B.,Gassmann, R.,Carter, A.P. Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383:eadk8544-eadk8544, 2024 Cited by PubMed: 38547289DOI: 10.1126/science.adk8544 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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