8PPU

Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches

8PPU の概要

• エントリーDOI: 10.2210/pdb8ppu/pdb
• EMDBエントリー: 17816
• 分子名称: DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... (7 entities in total)
• 機能のキーワード: polymerase, dna, replication, pold, archaea, editing, proofreading, exonuclease, nuclease, dna binding protein
• 由来する生物種: Pyrococcus abyssi GE5; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 321343.53

構造登録者

Betancurt-Anzola, L.,Martinez-Carranza, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L. (登録日: 2023-07-10, 公開日: 2023-12-20, 最終更新日: 2023-12-27)

• 主引用文献: Betancurt-Anzola, L.,Martinez-Carranza, M.,Delarue, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L.; Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.; Nat Commun, 14:8306-8306, 2023; PubMed: 38097591; DOI: 10.1038/s41467-023-44125-x

実験手法

ELECTRON MICROSCOPY (3.02 Å)