8POQ

Crystal structure of wolbachia leucyl-tRNA synthetase editing domain

Summary for 8POQ

• Entry DOI: 10.2210/pdb8poq/pdb
• Descriptor: Leucine--tRNA ligase (2 entities in total)
• Functional Keywords: leucine trna ligase, atp binding protein, trna aminoacylation for protein translation, cytosolic reaction catalysed: atp + l-leucine + trna(leu) = amp + diphosphate + l-leucyl-trna(leu), ligase
• Biological source: Wolbachia endosymbiont strain TRS of Brugia malayi
• Total number of polymer chains: 4
• Total formula weight: 79920.47

Authors

Palencia, A.,Lukarska, M. (deposition date: 2023-07-05, release date: 2024-06-12)

• Primary citation: Palencia, A.,Hoffmann, G.,Lukarska, M.,Clare, R.,Ward, S.,Taylor, M.A.,Ringkjobing Jensen, M.; Targeting A Microbiota Wolbachian Aminoacyl-tRNA Synthetase To Block Its Pathogenic Host; Science Advances, 2024

Experimental method

X-RAY DIFFRACTION (3 Å)