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8PMZ

HEV gt3 P domain in complex with glycan-insensitive nAb p61.15

Summary for 8PMZ
Entry DOI10.2210/pdb8pmz/pdb
DescriptorPro-secreted protein ORF2, scFv_p61.15, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordshev, p domain, non-glycosylated, glycan-insensitive, neutralizing antibody (nab), viral protein
Biological sourcePaslahepevirus balayani
More
Total number of polymer chains4
Total formula weight100621.91
Authors
Ssebyatika, G.,Krey, T. (deposition date: 2023-06-29, release date: 2024-07-10, Last modification date: 2024-11-13)
Primary citationSsebyatika, G.,Dinkelborg, K.,Stroeh, L.J.,Hinte, F.,Corneillie, L.,Hueffner, L.,Guzman, E.M.,Nankya, P.L.,Plueckebaum, N.,Prallet, S.,Mehnert, A.K.,Verhoye, L.,Juergens, C.,Steinmann, E.,Wedemeyer, H.,Viejo-Borbolla, A.,Dao Thi, L.V.,Pietschmann, T.,Luetgehetmann, M.,Meuleman, P.,Dandri, M.,Krey, T.,Behrendt, P.
A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.912 Å)
Structure validation

227344

건을2024-11-13부터공개중

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