8PLE
Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 15.
Summary for 8PLE
Entry DOI | 10.2210/pdb8ple/pdb |
Descriptor | Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE, N-(2-methoxy-5-methylphenyl)-N'-4H-1,2,4-triazol-4-ylurea, ... (4 entities in total) |
Functional Keywords | bi-functional, oxidoreductase, homodimer, flavoprotein |
Biological source | Schistosoma mansoni |
Total number of polymer chains | 2 |
Total formula weight | 132407.95 |
Authors | Ribeiro, L.,Montoya, B.O.,Moreira-Filho, J.T.,Bowyer, S.,Verma, A.,Neves, B.J.,Owens, R.J.,Andrade, C.H.,Silva-Jr, F.P.,Furnham, N. (deposition date: 2023-06-27, release date: 2024-01-31) |
Primary citation | de Souza Neto, L.R.,Montoya, B.O.,Brandao-Neto, J.,Verma, A.,Bowyer, S.,Moreira-Filho, J.T.,Dantas, R.F.,Neves, B.J.,Andrade, C.H.,von Delft, F.,Owens, R.J.,Furnham, N.,Silva-Jr, F.P. Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14:1582-1582, 2024 Cited by PubMed: 38238498DOI: 10.1038/s41598-024-52018-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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