8PKJ
Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5
Summary for 8PKJ
Entry DOI | 10.2210/pdb8pkj/pdb |
EMDB information | 17741 |
Descriptor | Histone H3 (Fragment), Histone H4, Histone H2A, ... (6 entities in total) |
Functional Keywords | nucleosome, nuclear receptor, nr5a2, dna binding protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 10 |
Total formula weight | 204174.50 |
Authors | Kobayashi, W.,Sappler, A.,Bollschweiler, D.,Kummecke, M.,Basquin, J.,Arslantas, E.,Ruangroengkulrith, S.,Hornberger, R.,Duderstadt, K.,Tachibana, K. (deposition date: 2023-06-26, release date: 2024-02-28, Last modification date: 2024-05-29) |
Primary citation | Kobayashi, W.,Sappler, A.H.,Bollschweiler, D.,Kummecke, M.,Basquin, J.,Arslantas, E.N.,Ruangroengkulrith, S.,Hornberger, R.,Duderstadt, K.,Tachibana, K. Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 31:757-766, 2024 Cited by PubMed: 38409506DOI: 10.1038/s41594-024-01239-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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