8PJK

ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex

Summary for 8PJK

• Entry DOI: 10.2210/pdb8pjk/pdb
• EMDB information: 17712 17747
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 140615.92

Authors

Schneider, J.,Gmeiner, P.,Rasmussen, T.,Boettcher, B. (deposition date: 2023-06-23, release date: 2024-05-29)

• Primary citation: Boettcher, B.; Discovery of a functionally selective serotonin 1A receptor agonist for the treatment of pain; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)