8PJH
Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation
Summary for 8PJH
Entry DOI | 10.2210/pdb8pjh/pdb |
Descriptor | Insulin (2 entities in total) |
Functional Keywords | insulin, precursor, dimer, hormone |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 5999.85 |
Authors | Schluckebier, G.,Johansson, E. (deposition date: 2023-06-23, release date: 2023-11-08, Last modification date: 2024-04-17) |
Primary citation | Kjeldsen, T.,Andersen, A.S.,Hubalek, F.,Johansson, E.,Kreiner, F.F.,Schluckebier, G.,Kurtzhals, P. Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42:464-478, 2024 Cited by PubMed: 37880066DOI: 10.1016/j.tibtech.2023.09.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report