8PJB

Cryo-EM structure of MLE in complex with UUC RNA and ADP

Summary for 8PJB

• Entry DOI: 10.2210/pdb8pjb/pdb
• EMDB information: 17703
• Descriptor: Dosage compensation regulator, RNA (5'-R(P*CP*UP*CP*UP*UP*UP*CP*UP*U)-3'), ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: rna helicase, rna binding protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 2
• Total formula weight: 134411.58

Authors

Jagtap, P.K.A.,Hennig, J. (deposition date: 2023-06-23, release date: 2023-11-01, Last modification date: 2024-06-05)

• Primary citation: Jagtap, P.K.A.,Muller, M.,Kiss, A.E.,Thomae, A.W.,Lapouge, K.,Beck, M.,Becker, P.B.,Hennig, J.; Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.; Mol.Cell, 83:4318-4333.e10, 2023; PubMed: 37989319; DOI: 10.1016/j.molcel.2023.10.026

Experimental method

ELECTRON MICROSCOPY (3.62 Å)