8PJ2

Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)

This is a non-PDB format compatible entry.

Summary for 8PJ2

• Entry DOI: 10.2210/pdb8pj2/pdb
• EMDB information: 17697
• Descriptor: Eukaryotic translation initiation factor 3 subunit B, 18S rRNA, 40S ribosomal protein S11, ... (55 entities in total)
• Functional Keywords: ribosome, translation, initiation, 48s, eif, human, eukaryotic, factor, codon, scanning, closed
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 53
• Total formula weight: 2253398.34

Authors

Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N. (deposition date: 2023-06-22, release date: 2024-08-14)

• Primary citation: Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N.; Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-024-01378-4

Experimental method

ELECTRON MICROSCOPY (3.4 Å)