8PD1
Pseudomonas aeruginosa FabF C164A mutant in complex with N-isopropyl-1H-imidazole-4-carboxamide
Summary for 8PD1
Entry DOI | 10.2210/pdb8pd1/pdb |
Related | 8CNE |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... (7 entities in total) |
Functional Keywords | inhibitor, protein-ligand complex, fabf, transferase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 89748.14 |
Authors | Georgiou, C.,Brenk, R.,Yadrykhinsky, V.,Espeland, L.O. (deposition date: 2023-06-11, release date: 2024-01-10) |
Primary citation | Georgiou, C.,Espeland, L.O.,Bukya, H.,Yadrykhinsky, V.,Haug, B.E.,Mainkar, P.,Brenk, R. New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-cwk25PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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