8PAY

Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 2.

8PAY の概要

• エントリーDOI: 10.2210/pdb8pay/pdb
• 分子名称: Beta sliding clamp, ACE-GLN-ALC-GLC-LEU-PHE, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: sliding clamp, covalent peptide, antibiotics, replication
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42806.97

構造登録者

Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.,wagner, J.,Guichard, G. (登録日: 2023-06-08, 公開日: 2024-03-13)

• 主引用文献: Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.Y.,Wagner, J.,Guichard, G.; Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.; Jacs Au, 4:432-440, 2024; PubMed: 38425897; DOI: 10.1021/jacsau.3c00572

実験手法

X-RAY DIFFRACTION (1.21 Å)