8PAV
Crystal structure of MST1 with a MAP4K1 SMOL inhibitor
Summary for 8PAV
Entry DOI | 10.2210/pdb8pav/pdb |
Descriptor | Serine/threonine-protein kinase 4 37kDa subunit, 1-[3,5-bis(fluoranyl)-4-[[3-(1,3-thiazol-5-yl)-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea, GLYCEROL, ... (5 entities in total) |
Functional Keywords | kinase, inhibitor, drug discovery, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 72487.81 |
Authors | |
Primary citation | Friberg, A.,Mowat, J.,Offringa, R. Identification and optimization of Azaindole based MAP4K1 Inhibitors and the discovery of BAY-405 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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