8P5Y

Artificial transfer hydrogenase with a Mn-12 cofactor and Streptavidin S112Y-K121M mutant

Summary for 8P5Y

Entry DOI	10.2210/pdb8p5y/pdb
Descriptor	Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)ethyl]pentanamide, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	artificial meatlloenzyme, transfer hydrogenase, manganese, metal binding protein
Biological source	Streptomyces avidinii
Total number of polymer chains	4
Total formula weight	68897.67
Authors	Lau, K.,Wang, W.,Pojer, F.,Larabi, A. (deposition date: 2023-05-24, release date: 2023-09-13, Last modification date: 2023-10-25)
Primary citation	Wang, W.,Tachibana, R.,Zou, Z.,Chen, D.,Zhang, X.,Lau, K.,Pojer, F.,Ward, T.R.,Hu, X. Manganese Transfer Hydrogenases Based on the Biotin-Streptavidin Technology. Angew.Chem.Int.Ed.Engl., 62:e202311896-e202311896, 2023 Cited by PubMed: 37671593 DOI: 10.1002/anie.202311896 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation