8P5Y

Artificial transfer hydrogenase with a Mn-12 cofactor and Streptavidin S112Y-K121M mutant

8P5Y の概要

• エントリーDOI: 10.2210/pdb8p5y/pdb
• 分子名称: Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)ethyl]pentanamide, MANGANESE (II) ION, ... (6 entities in total)
• 機能のキーワード: artificial meatlloenzyme, transfer hydrogenase, manganese, metal binding protein
• 由来する生物種: Streptomyces avidinii
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68897.67

構造登録者

Lau, K.,Wang, W.,Pojer, F.,Larabi, A. (登録日: 2023-05-24, 公開日: 2023-09-13, 最終更新日: 2023-10-25)

• 主引用文献: Wang, W.,Tachibana, R.,Zou, Z.,Chen, D.,Zhang, X.,Lau, K.,Pojer, F.,Ward, T.R.,Hu, X.; Manganese Transfer Hydrogenases Based on the Biotin-Streptavidin Technology.; Angew.Chem.Int.Ed.Engl., 62:e202311896-e202311896, 2023; PubMed: 37671593; DOI: 10.1002/anie.202311896

実験手法

X-RAY DIFFRACTION (1.88 Å)