8P5H
Kinase domain of mutant human ULK1 in complex with compound CCT241533
Summary for 8P5H
Entry DOI | 10.2210/pdb8p5h/pdb |
Related | 8P5G |
Descriptor | Serine/threonine-protein kinase ULK1, 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | autophagy, unc-like 1 kinase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65270.36 |
Authors | Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05) |
Primary citation | Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P. Crystal structures of ULK1 in complex with KCGS compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.941 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)