8P2Z

Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)

8P2Z の概要

• エントリーDOI: 10.2210/pdb8p2z/pdb
• EMDBエントリー: 17380
• 分子名称: Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: amino acid transporter, proline, slc6a20, ace2, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 165408.85

構造登録者

Li, H.Z.,Pike, A.C.W.,Chi, G.,Hansen, J.S.,Lee, S.G.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Chalk, R.,Moreira, T.,MacLean, E.M.,Marsden, B.,Bountra, C.,Burgess-Brown, N.A.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B. (登録日: 2023-05-16, 公開日: 2024-06-12, 最終更新日: 2024-07-10)

• 主引用文献: Li, H.Z.,Pike, A.C.W.,Lotsaris, I.,Chi, G.,Hansen, J.S.,Lee, S.C.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Burgess-Brown, N.A.,Vandenberg, R.J.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B.; Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.; Nat Commun, 15:5503-5503, 2024; PubMed: 38951531; DOI: 10.1038/s41467-024-48921-x

実験手法

ELECTRON MICROSCOPY (3.5 Å)