8P2R

Human Aldose Reductase Mutant A299G/L300A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)

8P2R の概要

• エントリーDOI: 10.2210/pdb8p2r/pdb
• 分子名称: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID, ... (5 entities in total)
• 機能のキーワード: human aldose reductase, har, aldo-keto-reductase, ligand, sar061, nadp+, diabetes, mutant a299g/l300a, transient pocket, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37125.06

構造登録者

Klee, L.-S.,Heine, A.,Klebe, G. (登録日: 2023-05-16, 公開日: 2024-06-12)

• 主引用文献: Klee, L.-S.,Heine, A.,Klebe, G.,Scheer, F.; Human Aldose Reductase Mutant A299G/L300A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid); To Be Published,

実験手法

X-RAY DIFFRACTION (1.25 Å)