8P2E

Homotypic interacting B1 fab bound to Chondroitin Sulfate A

Summary for 8P2E

• Entry DOI: 10.2210/pdb8p2e/pdb
• EMDB information: 17362
• Descriptor: B1 fab light, B1 fab heavy (2 entities in total)
• Functional Keywords: chondroitin sulfate a, sugar binding protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 8
• Total formula weight: 200327.50

Authors

Raghavan, S.S.R.,Dagil, R.,Wang, K.T.,Salanti, A. (deposition date: 2023-05-16, release date: 2024-06-05, Last modification date: 2024-09-11)

• Primary citation: Vidal-Calvo, E.E.,Martin-Salazar, A.,Choudhary, S.,Dagil, R.,Raghavan, S.S.R.,Duvnjak, L.,Nordmaj, M.A.,Clausen, T.M.,Skafte, A.,Oberkofler, J.,Wang, K.,Agerbaek, M.O.,Loppke, C.,Jorgensen, A.M.,Ropac, D.,Mujollari, J.,Willis, S.,Garcias Lopez, A.,Miller, R.L.,Karlsson, R.T.G.,Goerdeler, F.,Chen, Y.H.,Colaco, A.R.,Wang, Y.,Lavstsen, T.,Martowicz, A.,Nelepcu, I.,Marzban, M.,Oo, H.Z.,Orum-Madsen, M.S.,Wang, Y.,Nielsen, M.A.,Clausen, H.,Wierer, M.,Wolf, D.,Gogenur, I.,Theander, T.G.,Al-Nakouzi, N.,Gustavsson, T.,Daugaard, M.,Salanti, A.; Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.; Nat Commun, 15:7553-7553, 2024; PubMed: 39215044; DOI: 10.1038/s41467-024-51781-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)