8P0S

Crystal structure HR1 domain of Rho-associated coiled-coil protein kinases (ROCK-HR1)

8P0S の概要

• エントリーDOI: 10.2210/pdb8p0s/pdb
• 分子名称: Rho-associated protein kinase 1, 2,3-DIHYDROXY-1,4-DITHIOBUTANE (3 entities in total)
• 機能のキーワード: coiled coil, hr1, rho kinase, rock, prk, pkn, rhotekin, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32182.85

構造登録者

Dubey, B.N.,Dvorsky, R.,Gremer, L.,Vetter, I.R.,Schmitt, L.,Groth, G.,Ahmadian, M.R. (登録日: 2023-05-10, 公開日: 2023-06-21)

• 主引用文献: Dubey, B.N.,Amin, E.,Dvorsky, R.,Gremer, L.,Moll, J.M.,Wolff, M.,Graewert, M.,Tschapek, B.,Vetter, I.R.,Schmitt, L.,Svergun, D.,Raunser, R.,Groth, G.,Nagel-Steger, L.,Ahmadian, M.R.; Structural and functional insights into the p160 Rho-associated coiled-coil-containing protein kinase; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)