8OXY

Transglutaminase 3 without calcium in complex with DH patient-derived Fab DH63-B02

8OXY の概要

• エントリーDOI: 10.2210/pdb8oxy/pdb
• 分子名称: Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, Antibody fab fragment heavy chain, Antibody fab fragment light chain, ... (6 entities in total)
• 機能のキーワード: transglutaminase, tgm3, tg3, transglutaminase 3, enzyme, antibody, dermatitis herpetiformis, ighv3-9, iglv6-57, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 124746.64

構造登録者

Heggelund, J.E.,Sollid, L.M. (登録日: 2023-05-02, 公開日: 2023-10-18)

• 主引用文献: Heggelund, J.E.,Das, S.,Stamnaes, J.,Iversen, R.,Sollid, L.M.; Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3.; Nat Commun, 14:6216-6216, 2023; PubMed: 37798283; DOI: 10.1038/s41467-023-42004-z

実験手法

X-RAY DIFFRACTION (2 Å)