8OXV

Transglutaminase 3 zymogen in complex with DH patient-derived Fab DH63-B02

8OXV の概要

• エントリーDOI: 10.2210/pdb8oxv/pdb
• 分子名称: Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, Antibody Fab fragment Heavy chain, Antibody Fab fragment light chain, ... (7 entities in total)
• 機能のキーワード: transglutaminase, tgm3, tg3, transglutaminase 3, enzyme, zymogen, antibody, dermatitis herpetiformis, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 124310.81

構造登録者

Heggelund, J.E.,Sollid, L.M. (登録日: 2023-05-02, 公開日: 2023-10-18)

• 主引用文献: Heggelund, J.E.,Das, S.,Stamnaes, J.,Iversen, R.,Sollid, L.M.; Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3.; Nat Commun, 14:6216-6216, 2023; PubMed: 37798283; DOI: 10.1038/s41467-023-42004-z

実験手法

X-RAY DIFFRACTION (1.8 Å)