8OU1

Crystal structure of the SPOC domain of mouse SPOCD1

Summary for 8OU1

• Entry DOI: 10.2210/pdb8ou1/pdb
• Descriptor: SPOC domain-containing protein 1, CITRATE ANION (3 entities in total)
• Functional Keywords: pirna piwi dna methylation germline, gene regulation
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 32911.39

Authors

Heep, M.,Cook, A.G.,O'Carroll, D. (deposition date: 2023-04-21, release date: 2024-02-21, Last modification date: 2024-04-03)

• Primary citation: Zoch, A.,Konieczny, G.,Auchynnikava, T.,Stallmeyer, B.,Rotte, N.,Heep, M.,Berrens, R.V.,Schito, M.,Kabayama, Y.,Schopp, T.,Kliesch, S.,Houston, B.,Nagirnaja, L.,O'Bryan, M.K.,Aston, K.I.,Conrad, D.F.,Rappsilber, J.,Allshire, R.C.,Cook, A.G.,Tuttelmann, F.,O'Carroll, D.; C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line.; Mol.Cell, 84:1021-, 2024; PubMed: 38359823; DOI: 10.1016/j.molcel.2024.01.014

Experimental method

X-RAY DIFFRACTION (1.7 Å)