8OSC

Structure of Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1) bound to deoxyuridine 5'- monophosphate

Summary for 8OSC

• Entry DOI: 10.2210/pdb8osc/pdb
• Related: 8OS9
• Descriptor: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: deoxyribonucleoside 5'-monophosphate n-glycosidase activity, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 32696.62

Authors

Devi, S.,da Silva, R.G. (deposition date: 2023-04-18, release date: 2023-08-30, Last modification date: 2023-09-13)

• Primary citation: Devi, S.,Carberry, A.E.,Zickuhr, G.M.,Dickson, A.L.,Harrison, D.J.,da Silva, R.G.; Human 2'-Deoxynucleoside 5'-Phosphate N -Hydrolase 1: Mechanism of 2'-Deoxyuridine 5'-Monophosphate Hydrolysis.; Biochemistry, 62:2658-2668, 2023; PubMed: 37582341; DOI: 10.1021/acs.biochem.3c00369

Experimental method

X-RAY DIFFRACTION (1.42 Å)