8OS2

Structure of the human LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain in an unliganded state

8OS2 の概要

• エントリーDOI: 10.2210/pdb8os2/pdb
• 関連するPDBエントリー: 8ORX
• 分子名称: Lymphatic vessel endothelial hyaluronic acid receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: hyaluronan binding, cell migration, lymphatic system, cell adhesion
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16729.32

構造登録者

Ni, T.,Bannerji, S.,Jackson, D.J.,Gilbert, R.J.C. (登録日: 2023-04-17, 公開日: 2024-07-31)

• 主引用文献: Bano, F.,Bannerji, S.,Ni, T.,Green, D.E.,DeAngelis, P.L.,Paci, E.,Lepsik, M.,Jackson, D.J.,Gilbert, R.J.C.; A novel sliding interaction with hyaluronan underlies the mode of action of LYVE-1, the receptor for leucocyte entry and trafficking in the lymphatics; To be published,

実験手法

X-RAY DIFFRACTION (1.64 Å)