8ORP

Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose

8ORP の概要

• エントリーDOI: 10.2210/pdb8orp/pdb
• 関連するPDBエントリー: 8OR6
• 分子名称: Alpha-amylase A, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: alpha-amylase, alpha-1, 4-glucan-4-glucanohydrolase, beta- alpha-eight barrel, adaptation, hydrolase, inhibitor, acarbose
• 由来する生物種: Drosophila melanogaster (fruit fly)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 112640.84

構造登録者

Aghajari, N.,Haser, R. (登録日: 2023-04-16, 公開日: 2023-08-16)

• 主引用文献: Rhimi, M.,Da Lage, J.L.,Haser, R.,Feller, G.,Aghajari, N.; Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.; Molecules, 28:-, 2023; PubMed: 37513201; DOI: 10.3390/molecules28145327

実験手法

X-RAY DIFFRACTION (2 Å)