8OMK
hKHK-C in complex with ADP & fructose 1-phosphate
Summary for 8OMK
Entry DOI | 10.2210/pdb8omk/pdb |
Descriptor | Ketohexokinase, 1-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | ketohexokinase, khk, product complex, sugar kinase, sugar binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 69459.84 |
Authors | Ebenhoch, R.,Pautsch, A. (deposition date: 2023-03-31, release date: 2024-01-10, Last modification date: 2024-01-24) |
Primary citation | Heine, N.,Weber, A.,Pautsch, A.,Gottschling, D.,Upheus, I.,Baur, M.,Ebenhoch, R.,Nosse, B.,Kley, J. Discovery of BI-9787, a Potent Zwitterionic KHK-Inhibitor with Oral Bioavailability To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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