8OMD

Crystal structure of mKHK in complex with compound-4

Summary for 8OMD

Entry DOI	10.2210/pdb8omd/pdb
Descriptor	Ketohexokinase, compound (3 entities in total)
Functional Keywords	ketohexokinase, khk, product complex, sugar kinase, sugar binding protein
Biological source	Mus musculus (house mouse)
Total number of polymer chains	4
Total formula weight	140547.45
Authors	Ebenhoch, R.,Pautsch, A. (deposition date: 2023-03-31, release date: 2023-09-27, Last modification date: 2023-10-25)
Primary citation	Ebenhoch, R.,Bauer, M.,Romig, H.,Gottschling, D.,Kley, J.T.,Heine, N.,Weber, A.,Uphues, I.,Nar, H.,Pautsch, A. Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design. Acta Crystallogr D Struct Biol, 79:871-880, 2023 Cited by PubMed: 37712434 DOI: 10.1107/S2059798323006137 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation