8OKH

Crystal structure of Bdellovibrio bacteriovorus Bd1399

8OKH の概要

• エントリーDOI: 10.2210/pdb8okh/pdb
• 分子名称: DUF2807 domain-containing protein, GLYCEROL, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: unknown function
• 由来する生物種: Bdellovibrio bacteriovorus HD100
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38259.24

構造登録者

Caulton, S.G.,Lovering, A.L. (登録日: 2023-03-28, 公開日: 2023-10-25, 最終更新日: 2024-11-20)

主引用文献

Alexander, L.T.,Durairaj, J.,Kryshtafovych, A.,Abriata, L.A.,Bayo, Y.,Bhabha, G.,Breyton, C.,Caulton, S.G.,Chen, J.,Degroux, S.,Ekiert, D.C.,Erlandsen, B.S.,Freddolino, P.L.,Gilzer, D.,Greening, C.,Grimes, J.M.,Grinter, R.,Gurusaran, M.,Hartmann, M.D.,Hitchman, C.J.,Keown, J.R.,Kropp, A.,Kursula, P.,Lovering, A.L.,Lemaitre, B.,Lia, A.,Liu, S.,Logotheti, M.,Lu, S.,Markusson, S.,Miller, M.D.,Minasov, G.,Niemann, H.H.,Opazo, F.,Phillips Jr., G.N.,Davies, O.R.,Rommelaere, S.,Rosas-Lemus, M.,Roversi, P.,Satchell, K.,Smith, N.,Wilson, M.A.,Wu, K.L.,Xia, X.,Xiao, H.,Zhang, W.,Zhou, Z.H.,Fidelis, K.,Topf, M.,Moult, J.,Schwede, T.
Protein target highlights in CASP15: Analysis of models by structure providers.
Proteins, 91:1571-1599, 2023

PubMed Abstract: We present an in-depth analysis of selected CASP15 targets, focusing on their biological and functional significance. The authors of the structures identify and discuss key protein features and evaluate how effectively these aspects were captured in the submitted predictions. While the overall ability to predict three-dimensional protein structures continues to impress, reproducing uncommon features not previously observed in experimental structures is still a challenge. Furthermore, instances with conformational flexibility and large multimeric complexes highlight the need for novel scoring strategies to better emphasize biologically relevant structural regions. Looking ahead, closer integration of computational and experimental techniques will play a key role in determining the next challenges to be unraveled in the field of structural molecular biology.

PubMed: 37493353
DOI: 10.1002/prot.26545

実験手法

X-RAY DIFFRACTION (2.17 Å)