8OHA

Crystal structure of Leptospira interrogans GAPDH

8OHA の概要

• エントリーDOI: 10.2210/pdb8oha/pdb
• 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... (7 entities in total)
• 機能のキーワード: gapdh, leptospira interrogans, immune evasion, innate immunity, complement system, hydrolase
• 由来する生物種: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 304279.44

構造登録者

Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. (登録日: 2023-03-20, 公開日: 2023-08-23)

• 主引用文献: Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C.; The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity.; Front Immunol, 14:1190943-1190943, 2023; PubMed: 37409124; DOI: 10.3389/fimmu.2023.1190943

実験手法

X-RAY DIFFRACTION (2.37 Å)