8OGX

Beta-glucuronidase from Acidobacterium capsulatum in complex with inhibitor R3794

Summary for 8OGX

Entry DOI	10.2210/pdb8ogx/pdb
Descriptor	beta-glucuronidase from Acidobacterium capsulatum, (3~{S},4~{S})-4,5,5-tris(oxidanyl)piperidine-3-carboxylic acid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	beta-glucuronidase, hydrolase, acidobacterium capsulatum
Biological source	Acidobacterium capsulatum
Total number of polymer chains	1
Total formula weight	51086.69
Authors	Moran, E.M.,Davies, G.J.,Chen, C.,Nieuwendijk, E.V.,Wu, L.,Skoulikopoulou, F.,Riet, V.V.,Overkleeft, H.S.,Armstrong, Z. (deposition date: 2023-03-20, release date: 2024-01-10, Last modification date: 2024-01-24)
Primary citation	Chen, Y.,van den Nieuwendijk, A.M.C.H.,Wu, L.,Moran, E.,Skoulikopoulou, F.,van Riet, V.,Overkleeft, H.S.,Davies, G.J.,Armstrong, Z. Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B. J.Am.Chem.Soc., 146:125-133, 2024 Cited by PubMed: 38118176 DOI: 10.1021/jacs.3c04162 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation